靶点GPCR药出现 Targeted GPCR Drug Discovery
靶向治疗GPCR药品发展
GPCR详细介绍 GPCR(G蛋白酶偶连肾上腺素感觉)是口服药生产制造研究方向的国内明星靶标,到迄今为止为止有超700种将建口服药靶向治疗GPCR,约占到迄今为止为止所以将建口服药的1/3GPCR在无线信号转导中发挥出着本质功能:癌证、心理病、血糖值高的、阿尔茨海默病等危害性人類绿色的巨大病毒均与GPCR密切联系对应。既使,在GPCR大家族的800两个GPCR全体人员中,只是约达90个是求该的口服药靶点,涉及弃婴肾上腺素感觉其中的近300个全体人员在抗癌药物发掘因素兼有比较重要的实用价值与前景。
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GPCR蛋白质表达出来纯化 Letou乐投中文宝宝选择锲型的合拼球血清模块展现和纯化技术应用,在蜂类和哺乳期生物癌细胞展现系统方体积太累多种多样的生产经验,就可以制得高活力性、高溶解度的药靶点(GPCR球血清),使用中游模块判定、机构分折等制作化工作。
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源于速冻电镜的GPCR设计详解 Letou乐投中文性命借助的世界顶级的速冻自动化体视显微镜APP,探讨GPCR与口服药获选碳原子符合物的夺辩认率组成,为上下游AI口服药建立和依托于组成的口服药碳原子感觉提高高且关键性的组成微生命科学的信息。
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靶向性药物GPCR的微米免疫抗体性药物发现 Letou乐投中文生命安全有了稳重的微米技术表面抗原阳性中药会发现公司和羊驼饲养中心,可以用天然的库或表面抗原库建立要的调节GPCR靶点催化活性的新模块微米技术表面抗原阳性侯选中药。
Letou乐投中文生命力一对一助力器靶向药物GPCR的仿制药研发部 Letou乐投中文生活以的世界智领的微米表面抗原出现渠道为基本条件,通过求算动物学、构成动物学和氧分子药理学学等领先方法,创立了了靶点GPCR的食用的药物出现渠道,并全力于给出高的靶点GPCR微米表面抗原需求等CRO安全服务,为GPCR构成讲解及抗癌药物生产研发再添动力。
  • 具备站台式高渗透性GPCR表现、纯化及空间结构司法鉴定安全服务
  • GPCR系统验证通过精准服务
  • 冰冻电镜咨询中心
  • 源于GPCR组成的用药得知
  • 你们将在产品的每段时段.转成产品进度计划该报告
GPCR蛋白质成品所有
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
0PRM1 opioid receptor human HEK293/Sf9 full length
0PRL1 opioid receptor human HEK293/Sf9 full length
0PRK1 opioid receptor human HEK293/Sf9 full length
0PRD1 opioid receptor human HEK293/Sf9 full length
CCR2 Chemokine Receptor human HEK293/Sf9 full length
CCR4 Chemokine Receptor human HEK293/Sf9 full length
CCR5 Chemokine Receptor human HEK293/Sf9 full length
CCR6 Chemokine Receptor human HEK293/Sf9 full length
CCR7 Chemokine Receptor human HEK293/Sf9 full length
CCR9 Chemokine Receptor human HEK293/Sf9 full length
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
V2R Vasopressin receptor human HEK293/Sf9 full length
5-HT 1A Serotonin receptor human HEK293/5f9 full length
5-HT1B Serotonin receptor human HEK293/Sf9 full length
MTR1A Melatonin receptor human HEK293/Sf9 full length
MTR1B Melatonin receptor human HEK293/Sf9 full length
ADAZA Adrenergic receptol human HEK293/5f9 full length
ADA2B Adrenergic receptol human HEK293/Sf9 full length
ADA2C Adrenergic receptol human HEK293/5f9 full length
ADRB1 Adrenergic receptol human HEK293/Sf9 full length
ADRB2 Adrenergic receptol human HEK293/Sf9 full length
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
CXCR1 Chemokine Receptor human HEK293/Sf9 full length
CXCR2 Chemokine Receptor human HEK293/5f9 full length
CXCR3 Chemokine Receptor human HEK293/Sf9 full length
CXCR4 Chemokine Receptor human HEK293/5f9 full length
CXCR5 Chemokine Receptor human HEK293/Sf9 full length
DRD1 Dopamine receptor human HEK293/Sf9 full length
DRD2 Dopamine receptor human HEK293/Sf9 full length
DRD3 Dopamine receptor human HEK293/5f9 full length
MC3R Melanocortin receptor human HEK293/Sf9 full length
MC4R Melanocortin receptor human HEK293/Sf9 full length
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
OXTR Oxytocin receptor human HEK293/Sf9 full length
GHSR Ghrelin receptor human HEK293/Sf9 full length
CB1 Cannabinoid receptor human HEK293/Sf9 full length
CB2 Cannabinoid receptor human HEK293/Sf9 full length
CCKAR Cholecystokinin receptor human HEK293/Sf9 full length
CCKBR Cholecystokinin receptor human HEK293/Sf9 full length
0X1R Orexin receptor human HEK293/Sf9 full length
0X2R Orexin receptor human HEK293/Sf9 full length
PTGDR2 prostaglandin receptor human HEK293/Sf9 full length
PTGDR3 prostaglandin receptor human HEK293/Sf9 full length
PTGDR4 prostaglandin receptor human HEK293/Sf9 full length
Class B GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
VIP2R Vasoactive intestinal polypeptide rece ptor human HEK293/Sf9 full length
VIP1R Vasoactive intestinal polypeptide rece ptor human HEK293/Sf9 full length
AMY3R Amylin receptor human HEK293/Sf9 full length
AMY2R Amylin receptor human HEK293/Sf9 full length
AMY1R Amylin receptor human HEK293/Sf9 full length
CRF2R Corticotropinreleasing hormone receptor human HEK293/Sf9 full length
CRF1R Corticotropinreleasing hormone receptor human HEK293/Sf9 full length
AM2R Adrenomedullin receptor human HEK293/Sf9 full length
AMIR Adrenomedullin receptor human HEK293/Sf9 full length
PTH2R Parathyroid hormone receptor human HEK293/Sf9 full length
Class B GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
PTH1R Parathyroid hormone receptor human HEK293/Sf9 full length
CRHR2 Corticotropin releasing hormone rece ptor human HEK293/Sf9 full length
CRHR1 Corticotropin releasing hormone rece ptor human HEK293/Sf9 full length
CALCR Calcitonin receptor human HEK293/Sf9 full length
GHRHR Glucagon receptor human HEK293/Sf9 full length
GIPR Glucagon receptor human HEK293/Sf9
GLP2R Glucagon receptor human HEK293/Sf9 full length
GLP1R Glucagon receptor human HEK293/Sf9 full length
GCGR Glucagon receptor human HEK293/Sf9 full length
SCTR Secretin receptor human HEK293/Sf9 full length
Class C GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
CASR Calcium-sensing receptor human HEK293/Sf9 full length
GPRC6A opioid receptor human HEK293/Sf9 full length
GPRC5D Glucagon receptor human HEK293/Sf9 full length
GPRC5C Chemokine Receptor human HEK293/Sf9 full length
GPRC5B Glucagon receptor human HEK293/Sf9 full length
GPRC5A Glucagon receptor human HEK293/Sf9 full length
GPR179 opioid receptor human HEK293/Sf9 full length
GPR158 opioid receptor human HEK293/Sf9 full length
GPR156 opioid receptor human HEK293/Sf9 full length
TAS1R3 Taste receptor human HEK293/Sf9 full length
TAS1R2 Taste receptor human HEK293/Sf9 full length
Class C GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
TAS1R1 Taste receptor human HEK293/Sf9 full length
mGluR7 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR6 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR5 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR4 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR3 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR2 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluRI Metabotropic glutamate receptor human HEK293/Sf9 full length
GABBR2 Gamma-aminobutyric acid receptor human HEK293/Sf9 full length
GABBR1 Gamma-aminobutyric acid receptor human HEK293/Sf9 full length
CASR Calcium-sensing receptor human HEK293/Sf9 full length
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深圳市龙岗区南岭1983
创意小镇Letou乐投中文生命研究院

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